Photodynamic Therapy (PDT) – Frequently Asked Questions
What is photodynamic therapy and how does it work?
Photodynamic therapy (PDT) is a minimally invasive dermatology treatment that uses a combination of a topical photosensitizing agent and a specific wavelength of light to target abnormal or precancerous skin cells. Once applied, the photosensitizer is absorbed by damaged skin. When exposed to light, it produces a reaction that destroys these abnormal cells while preserving healthy surrounding tissue. PDT is typically performed in an outpatient setting and requires little to no downtime.
What is photodynamic therapy used for?
At Pure Dermatology in Austin, TX and Kyle, TX, we use photodynamic therapy most commonly to treat actinic keratoses (AKs)—precancerous lesions that develop from long-term sun exposure and may progress to squamous cell carcinoma if left untreated. PDT can also offer cosmetic benefits like improving sun-damaged skin, reducing fine lines, and evening out skin texture and tone as part of a facial rejuvenation treatment plan.
What should I expect during a photodynamic therapy treatment?
Your board-certified dermatologist will first evaluate your skin and give you detailed pre-treatment instructions. On the day of your procedure:
- A photosensitizing solution (commonly aminolevulinic acid or ALA) is applied to the affected areas.
- You’ll wait for 1–3 hours to allow the solution to absorb into the skin—this is called the incubation period.
- You can relax in the office, run errands indoors, or read during this time.
- Afterward, a medical-grade blue or red light is applied to activate the solution for approximately 15–20 minutes.
Is photodynamic therapy painful?
Most patients tolerate photodynamic therapy well. The application of the photosensitizer is painless, but during light activation, you may experience a tingling, burning, or stinging sensation. Your dermatologist can use cooling fans or numbing measures to reduce discomfort.
What is the recovery like after PDT?
After photodynamic therapy, it’s normal to experience redness, peeling, mild swelling, and sensitivity—similar to a sunburn. Most side effects resolve within a few days to a week. You must avoid all sun exposure for at least 48 hours after treatment, as the skin will be temporarily more reactive to UV rays.
Is Photodynamic Therapy Right for You?
Photodynamic therapy is a safe and effective way to treat precancerous lesions and sun-damaged skin without surgery. If you're looking for a targeted treatment for actinic keratosis in Austin and Kyle and the surrounding area including Buda and San Marcos, contact Pure Dermatology today to schedule a consultation with Dr. Christopher Chu or Dr. Chelsey Straight, board-certified dermatologists experienced in PDT skin therapy.
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